You'll need flour tortillas (8-10 inch size), cream cheese (plain or flavored), thinly sliced turkey breast, lettuce leaves, and any additional fillings you desire, such as thinly sliced cheese, bacon, avocado, or vegetables like sliced bell peppers or cucumber.
Lay the flour tortillas flat on a clean work surface. If the tortillas are cold, you can warm them slightly in the microwave for easier rolling.
Spread a layer of cream cheese evenly over each tortilla, covering the entire surface. The cream cheese acts as a flavorful spread and helps hold the pinwheels together.
Arrange the thinly sliced turkey breast in an even layer over the cream cheese-covered tortilla, leaving a small border around the edges. If you're adding additional fillings like cheese, bacon, or vegetables, layer them on top of the turkey.
Place a few lettuce leaves on top of the fillings. The lettuce adds freshness and texture to the pinwheels.
Starting from one edge, tightly roll up each tortilla into a spiral, making sure the fillings are compactly rolled inside. You may need to gently press down on the roll to secure it.
Using a sharp knife, slice each rolled tortilla into 1-inch thick pinwheels. For neat slices, you can trim off the uneven ends before slicing.
Arrange the turkey pinwheels on a serving platter and serve immediately, or store them in an airtight container in the refrigerator until ready to serve. If making ahead, cover the pinwheels with plastic wrap to prevent them from drying out.